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DC Field | Value | Language |
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dc.contributor.advisor | Vũ Đăng, Lưu | - |
dc.contributor.advisor | Đàm Thủy, Trang | - |
dc.contributor.author | Mai Thị, Ngọc | - |
dc.date.accessioned | 2022-10-28T01:56:36Z | - |
dc.date.available | 2022-10-28T01:56:36Z | - |
dc.date.issued | 2022-10 | - |
dc.identifier.uri | http://dulieuso.hmu.edu.vn/handle/hmu/3793 | - |
dc.description.abstract | This study aimed to describe the diagnostic performance of lung ultrasound (LUS) in detecting and semi-quantifying pneumothorax (PTX), using computed tomography (CT) as the reference standard. The study included 150 patients who underwent CT-guided transthoracic biopsy (TTB) for lung lesions. Within 30 minutes, two radiologists blinded to the participant’s prior information performed LUS in asymptomatic patients. The results showed that PTX was present on CT in 49/150 (32.3%) cases. LUS was positive in 40/150 (26.7%) patients, with a substantial agreement between the two radiologists (Cohen κ statistics = 0.8). The sensitivity and specificity of LUS were 100% (95%CI 97.6% to 100%) and 91.8% (95%CI 87.4% to 96.2%), respectively. Moreover, the positive and negative predictive values were 87.5% (95%CI 82.2% to 92.8%) and 96.4% (95%CI 92.4% to 98.9%), respectively. In the semi-quantification of PTX by LUS, the location of lung point was described in 36/49 (73.5%) patients. The sensitivity and specificity of this sign were 87.5% (95%CI 82.2% to 92.8%) and 96.4% (95%CI 92.4% to 98.9%), respectively. The positive and negative predictive values were 87.5% (95%CI 82.2% to 92.8%) and 96.4% (95%CI 92.4% to 98.9%), respectively. In conclusion, LUS is a susceptible and specific diagnostic method for diagnosing and semi-quantifying PTX. | vi_VN |
dc.description.tableofcontents | CONTENTS Acknowledgements i Declaration ii Contents iii Abbreviations vi List of tables vii List of figures viii INTRODUCTION 1 CHAPTER 1: LITERATURE REVIEW 3 1.1 Normal lungs anatomy on lung ultrasound 3 1.2. Lung ultrasound in the diagnosis of pneumothorax 4 1.2.1. Scanning technique and positioning 4 1.2.2. Normal findings on lung ultrasound 6 1.2.3. Diagnosis of PTX 8 1.2.4. The BLUE protocol 12 1.3. CT- guided transthoracic biopsy 14 1.3.1. Indication and contra-indication of CT- guided transthoracic biopsy 14 1.3.2. Process of CT-guided transthoracic biopsy 14 1.3.3. Common complications of CT-guided transthoracic biopsy 15 1.3.4. Management of PTX post-biopsy 16 1.4. Research history and remaining problems 18 1.4.1. International research 18 1.4.2. National research 19 CHAPTER 2: MATERIALS AND METHODS 20 2.1. Time and location 20 2.2. Study participants 20 2.3. Method of research 20 2.3.1. Study design 20 2.3.2. Sampling method 20 2.3.3. Description of imaging protocol 20 2.3.4. Flowchart of study 22 2.5. Study variables 23 2.5.1. Common variables 23 2.5.2. Variables of imaging features 23 2.5.3. Variables for diagnostic performance of LUS in comparison with CT 25 2.6. Statistical analysis 25 2.7. Bias and preventative measures 28 2.8. Ethics in research 28 CHAPTER 3: RESULTS 29 3.1. Patient’s characteristics 29 3.1.1. Gender 29 3.1.2. Age 29 3.1.3. Weight, height and BMI 29 3.2. Inter-reader reliability 31 3.3. Imaging features of pneumothorax on lung ultrasound 32 3.3.1. Confirmation of PTX on LUS 32 3.3.2. Size of PTX semi-quantification by LUS 35 3.4. Imaging features of pneumothorax on CT- scans 36 3.4.1. Confirmation of pneumothorax by CT: 36 3.4.2. Size of PTX on CT 38 3.5. Diagnostic performance of lung ultrasound in comparison with CT-scans 39 3.5.1. Confirmation of PTX 39 3.5.2. Size of PTX (semi-quantification) when lung point is presented 43 CHAPTER 4: DISCUSSION 44 4.1. General features of participants 44 4.2. Imaging features of pneumothorax on lung ultrasound 44 4.2.1. Normal findings on LUS 44 4.2.2. Confirmation of PTX on LUS 48 4.2.3. Size of PTX on LUS 52 4.3. Diagnostic performance of LUS in PTX compared with CT as the reference standard. 55 4.4. This study’s pros and cons. 56 CONCLUSION 59 RECOMMENDATION 61 REFERENCES | vi_VN |
dc.language.iso | en | vi_VN |
dc.subject | lung ultrasound | vi_VN |
dc.subject | pneumothorax | vi_VN |
dc.subject | CT-guided transthoracic biopsy | vi_VN |
dc.subject | diagnostic performance | vi_VN |
dc.subject | semi-quantification | vi_VN |
dc.title | Diagnostic performance of lung ultrasound in detecting pneumothorax after CT- guided transthoracic biopsy | vi_VN |
dc.type | Thesis | vi_VN |
Appears in Collections: | Luận văn bác sĩ nội trú |
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