Please use this identifier to cite or link to this item: http://dulieuso.hmu.edu.vn/handle/hmu/3542
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dc.contributor.advisorVU, VAN GIAP-
dc.contributor.advisorNGUYEN, TOAN THANG-
dc.contributor.authorNGUYEN, VU HOANG VIET-
dc.date.accessioned2022-02-24T04:36:15Z-
dc.date.available2022-02-24T04:36:15Z-
dc.date.issued2020-
dc.identifier.urihttp://dulieuso.hmu.edu.vn/handle/hmu/3542-
dc.description.abstractAnesthesia for bronchoscopy poses unique challenges for the anesthesiologists. By definition, bronchoscopy is an endoscopic technique to visualize the inside of the airways for diagnostic and therapeutic purposes. This procedure needs specific technical precision because both the anesthesiologist and operator share the same working space, that is, the airway. Advances in technology and instrumentation have made it a much safer procedure1 . Flexible bronchoscopy is usually done by respiratory physicians and is the gold standard for visualising the airway and performing various diagnostic and therapeutic interventions. Rigid bronchoscopy usually requires general anaesthesia while flexible bronchoscopy can be done under sedation supplemented with topical anaesthesia1 . Obstructive sleep apnoea (OSA) is caused by repetitive partial or complete obstruction of the upper airway, characterized by episodes of breathing cessation during sleep, which last 10 or more seconds. From the anaesthesiologist’s standpoint, patients with OSA pose significant problems in the perioperative period, including difficult airways, sensitivity to anaesthetic agents, and postoperative adverse events. OSA has been associated with an increase in postoperative complications , and is an independent risk factor for increased morbidity and mortality. A significant proportion of patients with OSA are undiagnosed before surgery. It is therefore increasingly recognized as a significant perioperative problem2,3 . In Respiratory Centre Bach Mai hospital, we perform both flexible bronchoscopy and rigid bronchoscopy under intravenous and general anaesthesia. Flexible bronchoscopy cases account for above 90% of 2 bronchoscopy so we do this research to find out risk factors and complication of obstructive sleep apnea among patients undergoing bronchoscopy with intravenous anesthesia at Bach Mai Hospital. Our objectives were: 1. To evaluate the characteristics of patients at a risk of having obstructive sleep apnea among patients undergoing bronchoscopy with intravenous anesthesia. 2. Relation between risk factors of obstructive sleep apnoea and critical respiratory events among patients undergoing bronchoscopy with intravenous anaesthesia at Bach Mai hospital.vi_VN
dc.description.tableofcontentsCONTENTS Introduction.................................................................................................. 1 Chapter I: Overviews................................................................................... 3 1.1. Flexible bronchoscopy and its unpleasant............................................. 3 1.2. Anesthesia for flexible bronchoscopy and complications ..................... 4 1.3. Obstructive sleep apnea ...................................................................... 10 1.3.1 Risk factors and associated conditions........................................... 10 1.3.2 Clinical features ............................................................................ 12 1.3.3 Screening for OSA ........................................................................ 18 Chapter II: Materials and Methods .......................................................... 22 2.1 Participants.......................................................................................... 22 2.1.1 Inclusion criteria............................................................................ 22 2.1.2 Exclusion criteria........................................................................... 22 2.2 Study design........................................................................................ 22 2.2.1 Study method ................................................................................ 22 2.2.2 Location and time of research........................................................ 22 2.3. Sample ............................................................................................... 22 2.4. Data collection ................................................................................... 23 2.5 Variable study ..................................................................................... 27 2.6. Outcome assessment........................................................................... 31 2.7. Statistical analysis .............................................................................. 31 2.8. Limit, bias, and bias controlling ......................................................... 31 2.8.1. Limit ............................................................................................ 31 2.8.2. Bias.............................................................................................. 31 2.8.3. Bias controlling ............................................................................ 31 2.9. Ethics in the research.......................................................................... 32 CHAPTER 3: RESULT ............................................................................. 33 3.1 Characteristics of patients undergoing flexible bronchoscopy with intravenous anesthesia screening risk of OSA by STOP-Bang questionnaires. 33 3.1.1. Patients’ characteristics ................................................................ 33 3.1.2. Clinical symptoms........................................................................ 35 3.2 Some factors associated with OSA ...................................................... 36 3.2.1 Body mass index (BMI) ................................................................ 36 3.2.2. Frequency of snoring.................................................................... 36 3.2.3 Observed apneic episode ............................................................... 37 3.2.4. Neck circumference...................................................................... 37 3.2.5 Mallampati class............................................................................ 38 3.3 Intravenous anesthesia bronchoscopy and its complications................ 38 3.3.1 Changes in SpO2........................................................................... 39 3.3.2 Jaw-thrust maneuver and OSA ...................................................... 41 3.3.3. Changes in hemodynamic variables.............................................. 42 3.3.4. Discomfort after bronchoscopy 24h.............................................. 43 CHAPTER 4: DISCUSSION ..................................................................... 44 4.1. Characteristics of patients undergoing flexible bronchoscopy with intravenous anesthesia screening risk of OSA by STOP-Bang questionnaire. . 44 4.1.1 Proportion of patients with risk of OSA based on STOP-Bang questionnaire .......................................................................................... 44 4.1.2 Patient’s characteristics ................................................................. 45 4.1.3 Clinical symptoms......................................................................... 47 4.2 Some factors associated with OSA ...................................................... 47 4.2.1 Body mass index (BMI) ................................................................ 47 4.1.2 Neck circumference....................................................................... 48 4.1.3 Frequency of snoring..................................................................... 48 4.1.4 Mallampati class............................................................................ 48 4.3 Intravenous anesthesia bronchoscopy and its complications................ 49 4.3.1 ASA and risk of OSA.................................................................... 49 4.3.2 Changes in SpO2........................................................................... 50 4.3.3 Changes in hemodynamic variables............................................... 51 4.3.4 Discomfort after bronchoscopy 24h............................................... 53 CONCLUSION........................................................................................... 54 REFERENCESvi_VN
dc.language.isoenvi_VN
dc.subjectRespiratory medicinevi_VN
dc.subject62722005vi_VN
dc.subjectHô hấpvi_VN
dc.titleRELATION BETWEEN RISK FACTORS OF OBSTRUCTIVE SLEEP APNEA AND CRITICAL RESPIRATORY EVENTS AMONG PATIENTS UNDERGOING BRONCHOSCOPY WITH INTRAVENOUS ANESTHESIA AT BACH MAI HOSPITALvi_VN
dc.typeThesisvi_VN
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